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Possible link between BRCA1 and BRCA2 mutations and rare breast implant-associated lymphoma

https://www.facingourrisk.org/XRAY/BIA-ALCL-among-BRCA-carriers-with-breast-implants
Full article: https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2025016810/537761/BRCA1-2-impact-on-the-development-of-implant

The causes of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare cancer that develops near implants, are unknown. Results from this study suggest that people with an inherited mutation in BRCA1 or BRCA2 may be at increased risk for BIA-ALCL. However, because very few cases of BIA-ALCL occurred among participants, more research is needed to confirm or refute this finding. (Posted 7/14/2025)

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FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.