Study: Endometrial cancer risk for people with BRCA1 and BRCA2 mutations

https://www.facingourrisk.org/XRAY/endometrial-cancer-risk-BRCA1-BRCA2-carriers

Full article: https://www.gynecologiconcology-online.net/article/S0090-8258(24)01052-7/abstract

This study looked at how often endometrial cancer occurred in people with BRCA1 or BRCA2 mutations to better understand how BRCA mutations affect the risk of endometrial cancer. The researchers also asked whether known risk factors for endometrial cancer impact the frequency of endometrial cancer in people with BRCA1 or BRCA2 mutations. Findings from the study highlight the importance of shared conversations between patients and providers regarding risk monitoring and preventive options. (posted 10/7/25)

Questions To Ask Your Health Care Provider

What are my risk factors for endometrial cancer (e.g., age, body weight, tamoxifen use)?
If oophorectomy is recommended, should I also have a hysterectomy to reduce my endometrial cancer risk? What are the risks and benefits of this surgery?
What are the signs and symptoms of endometrial cancer?

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.