Hereditary cancer mutations among people with multiple myeloma
https://www.facingourrisk.org/XRAY/hereditary-multiple-myeloma
Full article: https://pmc.ncbi.nlm.nih.gov/articles/PMC11528192/
People with multiple myeloma who have inherited gene mutations are more likely to have had another cancer previously and may respond better to certain treatments than people with multiple myeloma who do not have inherited mutations. Individuals with an inherited BRCA1 and BRCA2 mutation may have a slightly increased risk for multiple myeloma, but more research is needed to confirm this. (Posted 4/23/25)
Questions To Ask Your Health Care Provider
- I have multiple myeloma:
- Would genetic testing be useful in planning my treatment?
- Would genetic testing be useful for my family?
- I had cancer before being diagnosed with multiple myeloma. Are the cancers I have had related to each other?
- I have a mutation in a hereditary cancer gene. Are there any targeted treatments that I should consider for my multiple myeloma?
- Given my personal and family cancer history, should I have genetic testing? What are the risks and benefits?
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.