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PARP inhibitors withdrawn as third-line or later treatment for recurrent ovarian cancer

https://www.facingourrisk.org/XRAY/PARP-inhibitors-withdrawn-for-recurrent-ovarian-cancer
Full article: https://www.annalsofoncology.org/article/S0923-7534(22)02497-8/pdf

Survival data from a clinical trial signaled that PARP inhibitors may not work as well as chemotherapy for patients with recurrent ovarian cancer who have received three or more lines of treatment. As a result, FDA approvals have been withdrawn for PARP inhibitors in this setting.  This does not affect PARP inhibitor approvals for use as maintenance therapy for ovarian cancer. (Posted 10/4/22)

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The following are studies looking at PARP inhibitors and similar agents for treating people with ovarian cancer.  

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About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.