Study uses mice and brains from deceased Alzheimer’s patients to assess BRCA1 involvement

https://www.facingourrisk.org/XRAY/alzheimers-and-brca

Full article: https://www.nature.com/ncomms/2015/151130/ncomms9897/full/ncomms9897.html

Researchers noted reduced levels of BRCA1 protein in the brains of mice and deceased Alzheimer's patients. While this study is interesting early work on the biology of Alzheimer's disease, the focus was primarily Alzheimer's disease, rather than the effect of BRCA1 mutations on Alzheimer's. Therefore, this study's observation may be something that is seen in Alzheimer's patients, but does not necessarily cause the disease. No studies suggest that BRCA1 mutation carriers are at increased risk for Alzheimer's disease. (12/22/2015)

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