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How many children with cancer have mutations in genes that increase cancer risk?

https://www.facingourrisk.org/XRAY/childhood-cancer-and-mutations
Full article: https://www.nejm.org/doi/full/10.1056/NEJMoa1508054

Many genes are associated with increased cancer risk in adults, but it is unclear how common these mutations are in children with cancer. This study found that about 9% of children with cancer carry mutations in a gene that is known to increase cancer risk. Over half of the mutations were in the TP53 gene, which is associated with increased cancer risk at a young age and increased risk of breast cancer in adults. (12/15/2015)

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FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.