Inherited mutations in metastatic breast cancer patients
https://www.facingourrisk.org/XRAY/inherited-mutations-in-metastatic-breast-cancer-patients
Full article: https://jamanetwork.com/journals/jamaoncology/article-abstract/2749176
Recent research shows that a significant portion of patients with metastatic breast cancer have harmful mutations in a gene associated with hereditary breast cancer and increased breast cancer risk. (9/26/19)
Questions To Ask Your Health Care Provider
- I have metastatic breast cancer; should I have genetic testing?
- Who should I contact to have genetic testing?
- If I have a mutation in a gene that is associated with increased breast cancer risk, how might that change my treatment for metastatic breast cancer?
- What are the risks and benefits of genetic testing for me and my family?
Open Clinical Trials
The following studies involve genetic testing in people with advanced cancers:
- NCT01775072: Genomic Profiling in Cancer Patients. This study aims to better understand how genetic changes affect cancer outcomes. Researchers are looking at inherited and tumor mutations .
- NCT03503097: Genetic testing for men with metastatic prostate cancer (GENTleMEN). This study determines if online genetic education and testing with online genetic counseling is an acceptable method of providing genetic testing to men with metastatic prostate cancer.
- NCT03665295: PROMPT. The goal of the PROMPT Registry is to follow people with mutations or variants in genes found on genetic testing panels so that patients physicians and researchers can more clearly understand lesser-known risks.
- NCT04353973: A Randomized Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Breast, Ovarian, Prostate and Pancreatic Cancer Patients (E-Reach). This study explores the use of web options to increase access to testing AND patients in this study can get genetic counseling and testing in their home.
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.