Frequency of inherited mutations linked to breast cancer are similar in Black and white women
https://www.facingourrisk.org/XRAY/mutations-in-Black-and-white-women-with-breast-cancer
Full article: https://jamanetwork.com/journals/jamaoncology/article-abstract/2780262
The CARRIERS study looked at the rate of inherited mutations in women with and without breast cancer. In an extension of the CARRIERS study, researchers found no difference in the frequency of inherited mutations in breast cancer genes among Black and white women with breast cancer. A few individual genes differed in frequency: BRCA2 and PALB2 mutations were seen more often in Black women, while CHEK2 mutations were seen less often. Researchers concluded that race should not be used to determine who is referred for genetic testing. (posted 8/13/21)
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Questions To Ask Your Health Care Provider
- Should I have genetic testing for inherited mutations in cancer genes?
- How do I get genetic counseling?
- If I have an inherited mutation, what surveillance or preventive options do you recommend for me?
- I have a gene that is linked to an increased risk of breast cancer. Are there other cancer risks I should consider?
- My insurance won’t cover genetic testing. How can I get low-cost genetic testing?
Open Clinical Trials
The following clinical research studies focus on addressing health disparities in cancer.
- NCT04854304: Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts. This study is looking at how effectively a FAST breast MRI can successfully detect breast cancer in Black women with dense breasts.
- NCT03640208: Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans. This research will study a community-based intervention to educate and overcome barriers to screening among African Americans who are 45 years or older with no personal or family history of colorectal cancer or inflammatory bowel disease.
- NCT04392050: A Community-Based Educational Intervention to Improve Colorectal Cancer Screening. This study will look at what makes it easy or difficult for underserved populations to have colorectal cancer screenings, with a focus on African American, Latinx and Asian people.
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.