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Featured Studies Results

Treating Advanced MSI-High or dMMR Cancers Using the Targeted Therapy MOMA-341 Given Alone or In Combination with Standard Therapies

https://www.facingourrisk.org/research-clinical-trials/study/356/treating-advanced-msi-high-or-dmmr-cancers-using-the-targeted-therapy-moma-341-given-alone-or-in-combination-with-standard-therapies

Clinicaltrials.gov identifier:
NCT06974110 (https://clinicaltrials.gov/show/NCT06974110)

Treatment
Treatment study for people with advanced or metastatic cancers


Study of an Investigational Drug, E7386 Plus Lenvatinib in People with Endometrial Cancer after Chemotherapy and Immunotherapy

https://www.facingourrisk.org/research-clinical-trials/study/355/study-of-a-new-drug-e7386-in-combination-with-lenvatinib-in-people-with-previously-treated-endometrial-cancer

Clinicaltrials.gov identifier:
NCT04008797 (https://clinicaltrials.gov/show/NCT04008797)

Treatment
Treatment study for people with previously treated endometrial cancer


Using a Shorter Type of MRI as a Screening Tool for People at High Risk for Prostate Cancer

https://www.facingourrisk.org/research-clinical-trials/study/353/using-biparametric-magnetic-resonance-imaging-mri-as-a-screening-tool-for-those-at-high-risk-for-prostate-cancer

Clinicaltrials.gov identifier:
NCT05384535 (https://clinicaltrials.gov/show/NCT05384535)

Prevention
Screening for people at high risk for prostate cancer


NePtune: Using PARP Inhibitors Before Surgery in Localized Prostate Cancer

https://www.facingourrisk.org/research-clinical-trials/study/314/neptune-using-parp-inhibitors-before-surgery-in-localized-prostate-cancer

Clinicaltrials.gov identifier:
NCT05498272 (https://clinicaltrials.gov/show/NCT05498272)

Treatment
Treatment study for people with intermediate- or high-risk prostate cancer with certain tumor mutations


Treating Advanced Cancers with BRCA or Other Related Gene Mutations Using Targeted Therapy MOMA-313 Alone or In Combination with the PARP Inhibitor Olaparib

https://www.facingourrisk.org/research-clinical-trials/study/328/treating-advanced-cancers-with-dna-repair-mutations-using-moma-313-alone-or-in-combination-with-the-parp-inhibitor-olaparib

Clinicaltrials.gov identifier:
NCT06545942 (https://clinicaltrials.gov/show/NCT06545942)

Treatment
Treatment study for people with advanced or metastatic cancers


Pfizer Clinical Trials for Metastatic Prostate Cancer are Now Enrolling

https://www.facingourrisk.org/research-clinical-trials/study/321/pfizer-clinical-trials-for-metastatic-prostate-cancer-are-now-enrolling

Treatment
Men aged 18 years or older with metastatic prostate cancer


Learning about the Needs of Autistic People Related to Breast Cancer Screening and Testing

https://www.facingourrisk.org/research-clinical-trials/study/341/learning-about-the-needs-of-autistic-people-related-to-breast-cancer-screening-and-testing

Surveys, Registries, Interviews
Online survey for autistic people with or at high risk for breast cancer


Hormone Replacement Therapy After Risk-Reducing Surgery in Individuals at Increased Risk for Breast Cancer: The Patient Perspective

https://www.facingourrisk.org/research-clinical-trials/study/337/hrt-after-risk-reducing-surgery-in-women-at-increased-risk-for-breast-cancer-the-patient-perspective

Surveys, Registries, Interviews
Survey for individuals with a BRCA1, BRCA2, PALB2, RAD51C, RAD51D mutation


Research Study on the Genetics of Breast Cancer

https://www.facingourrisk.org/research-clinical-trials/study/317/research-study-on-the-genetics-of-breast-cancer

Clinicaltrials.gov identifier:
NCT06773897 (https://clinicaltrials.gov/show/NCT06773897)

Surveys, Registries, Interviews
A registry for anyone aged 18 and older who lives in the United States


Study of a New Investigational Inhibitor to Treat People with Advanced Solid Tumors

https://www.facingourrisk.org/research-clinical-trials/study/300/study-of-a-new-investigationai-inhibitor-to-treat-people-with-advanced-solid-tumors

Clinicaltrials.gov identifier:
NCT05932862 (https://clinicaltrials.gov/show/NCT05932862)

Treatment
Treatment study for people with advanced solid tumors


Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer (LAP100)

https://www.facingourrisk.org/research-clinical-trials/study/347/testing-higher-dose-radiation-therapy-for-locally-advanced-pancreatic-cancer

Clinicaltrials.gov identifier:
NCT06958328 (https://clinicaltrials.gov/show/NCT06958328)

Treatment
Radiation treatment study for people with locally advanced pancreatic cancer


Pancreatic Cancer Screening Study for People with ATM, BRCA1, BRCA2 or PALB2 Mutations

https://www.facingourrisk.org/research-clinical-trials/study/330/screening-study-for-pancreatic-cancer

Clinicaltrials.gov identifier:
NCT05058846 (https://clinicaltrials.gov/show/NCT05058846)

Prevention
Pancreatic cancer screening study for people with ATM, BRCA1, BRCA2 or PALB2 mutations


PREVAIL Study: A Genetic Education and Genetic Testing Study for African American Men with Prostate Cancer or with a Strong Family History of Cancer

https://www.facingourrisk.org/research-clinical-trials/study/351/prevail-study-a-genetic-education-and-genetic-testing-study-for-african-american-men-with-prostate-cancer-or-with-a-strong-family-history-of-cancer

Surveys, Registries, Interviews
Study for African American men with prostate cancer or with a strong family history of cancer


Understanding the Cancer Journey: A Survey of Patient Experiences and Emotional Impact

https://www.facingourrisk.org/research-clinical-trials/study/357/understanding-the-cancer-journey-a-survey-of-patient-experiences-and-emotional-impact

Surveys, Registries, Interviews
Survey for people diagnosed with lung, liver, pancreatic or thyroid cancer


Studying a New PARP Inhibitor and Hormonal Therapy to Treat HER2-negative, HR-positive Metastatic Breast Cancer with a BRCA1, BRCA2, or PALB2 Mutation (EvoPAR BR01)

https://www.facingourrisk.org/research-clinical-trials/study/349/studying-a-new-parp-inhibitor-and-hormonal-therapy-to-treat-her2-negative-hr-positive-metastatic-breast-cancer-with-a-brca1-brca2-or-palb2-mutation-evopar-br01

Clinicaltrials.gov identifier:
NCT06380751 (https://clinicaltrials.gov/show/NCT06380751)

Treatment
Treatment study for HER2-negative, HR-positive metastatic breast cancer with a BRCA1, BRCA2 or PALB2 mutation


An Online Program to Help Asian American Breast Cancer Survivors Manage Pain and Depression

https://www.facingourrisk.org/research-clinical-trials/study/352/an-online-program-to-help-asian-american-breast-cancer-survivors-manage-pain-and-depression

Clinicaltrials.gov identifier:
NCT06085313 (https://clinicaltrials.gov/show/NCT06085313)

Quality of Life
An online program to help Asian American breast cancer survivors manage pain and depression


Treating Advanced or Metastatic Cancers with a New PARP1 Inhibitor (GS-0201) Alone or Combined with Other Drugs

https://www.facingourrisk.org/research-clinical-trials/study/350/treating-advanced-or-metastatic-cancers-with-the-new-parp-inhibitor-alone-or-combined-with-other-drugs

Clinicaltrials.gov identifier:
NCT06167317 (https://clinicaltrials.gov/show/NCT06167317)

Treatment
Treatment study for people with advanced or metastatic solid tumors


Understanding the Needs of LGBTQIA+ Caregivers Supporting People with Cancer

https://www.facingourrisk.org/research-clinical-trials/study/346/understanding-the-needs-of-lgbtqia-caregivers-supporting-people-with-cancer

Surveys, Registries, Interviews
Survey and interview for LGBTQIA+ caregivers supporting people with cancer


About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.