Upright MRI for Prostate Cancer Screening

https://www.facingourrisk.org/research-clinical-trials/study/259/upright-mri-for-prostate-cancer-screening

Clinicaltrials.gov identifier:
NCT03474913 (https://clinicaltrials.gov/show/NCT03474913)

Prevention
Screening for prostate cancer using upright MRI

Study Contact Information:

For additional information, please contact:

Study Director: Dara Lundon (212) 241-0751 Dara.Lundon@mountsinai.org

About the Study

This study will compare the effectiveness of an upright magnetic resonance imaging (MRI) compared to prostate specific antigen (PSA) and current MRI imaging for prostate cancer screening.

What the Study Involves

Participants will have a standard of care MRI as well as an upright, seated MRI. After each MRI, participants will be asked to fill out questionnaires to assess their comfort level during the scans. If something suspicious is found on either scan, participants may have an ultrasound guided biopsy of the prostate, a way to sample and test prostate tissue for cancer. Researchers will check in with the participants every 6 months for 5 years.

Study Site

New York

New York
Icahn School of Medicine at Mount Sinai
Principal Investigator: Ash Tewari, MD
Contact: Dara Lundon (212) 241-0751 Dara.Lundon@mountsinai.org

Lead Researcher

Ash Tewari: Icahn School of Medicine at Mount Sinai

This Study is Open To:

Men 18 years and older who:

Are at risk of prostate cancer and have been told to have a prostate MRI
Can undergo all parts of the study including ultrasound guided biopsy
Can tolerate general or spinal anesthesia
Ability to understand and the willingness to sign a written informed consent and to comply with the protocol.

This Study is Not Open To:

Those who do not meet the criteria defined above and individuals who:

Have been treated with 5-alpha-reductase inhibitors (marketed as Proscar, Propecia, or Avoadart) within 6 months before beginning the study
Have had a previous prostate biopsy, prostate surgery, or treatment for prostate cancer
Have a urinary tract infection or history of acute prostatitis, inflammation of the prostate, within the last 3 months
Cannot have an MRI

About FORCE

FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.