Carboplatin Chemotherapy before Surgery for Patients with High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation
https://www.facingourrisk.org/research-clinical-trials/study/286/swog-s2210-carboplatin-chemotherapy-before-surgery-for-patients-with-high-risk-prostate-cancer-and-an-inherited-brca1-or-brca2-gene-mutation
Clinicaltrials.gov identifier:
NCT05806515 (https://clinicaltrials.gov/show/NCT05806515)
Treatment
Treatment before surgery for people with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation
Study Contact Information:
Primary Investigator: Heather H. Cheng, MD PhD
Call 1-800-4-Cancer (ask about S2210)
About the Study
This study tests the effectiveness of taking the medication carboplatin between prostate cancer diagnosis and surgery to remove the prostate. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. After surgery participants will follow up with the study team over three years to answer questions about their medical history since surgery.
What the Study Involves
The carboplatin is given intravenously (injected into the vein), once every 3 weeks for up to 4 doses. Then, surgery to remove the prostate will be performed and the study team will follow how the participant does with a few more visits until 3 years after surgery.
Participants will be asked to bank a tissue sample from the prostate removal for use in future studies, but this is not a requirement to participate. Participants also undergo collection of blood samples throughout the trial.
PRIMARY OBJECTIVE:
- To check how effective carboplatin treatment is for patients with aggressive prostate cancer who have BRCA1 or BRCA2 gene mutations. We'll do this by looking at the records of patients who had surgery after receiving this treatment to see if they had a complete response.
SECONDARY OBJECTIVES:
- To evaluate how long patients stay free from prostate specific antigen (PSA) progression after prostate surgery, both overall and specifically, at the 3-year landmark.
- To evaluate how long patients live without their cancer spreading to other parts of their body (metastases) as well as their overall survival.
- To evaluate how often and how severe the side effects are for patients who get carboplatin treatment before having their prostate removed surgically.
BANKING OBJECTIVE:
- To bank (save) samples for later studies that will help us understand more about prostate cancer.
Study Locations
(Check study website for updated information, SWOG.org/S2210)
United States
Alaska
Anchorage
Alaska Women's Cancer Care
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Anchorage Oncology Centre
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Alaska Breast Care and Surgery LLC
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Katmai Oncology Group
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Anchorage Associates in Radiation Medicine
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Alaska Oncology and Hematology LLC
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Providence Alaska Medical Center
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Anchorage Radiation Therapy Center
Contact: Site Public Contact
Phone: 907-212-6871
Email: AKPAMC.OncologyResearchSupport@providence.org
Arizona
Phoenix
Cancer Center at Saint Joseph's
Contact: Site Public Contact
Phone: 602-406-0777
Email: Research-cancerinstitute@dignityhealth.org
California
Arroyo Grande
Mission Hope Medical Oncology - Arroyo Grande
Contact: Site Public Contact
Phone: 805-219-4673
Email: ResearchInstituteInquiries@CommonSpirit.org
Burbank
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Contact: Site Public Contact
Phone: 818-847-4793
Email: Najee.Boucher@providence.org
Carmichael
Mercy San Juan Medical Center
Contact: Site Public Contact
Phone: 916-556-3301
Email: OncologyResearch@DignityHealth.org
Mercy Cancer Center Carmichael
Contact: Site Public Contact
Email: protocols@swog.org
Duarte
City of Hope Comprehensive Cancer Center
Contact: Site Public Contact
Phone: 800-826-4673
Email: becomingapatient@coh.org
Elk Grove
Mercy Cancer Center - Elk Grove
Contact: Site Public Contact
Phone: 916-556-3301
Email: OncologyResearch@DignityHealth.org
Irvine
City of Hope at Irvine Lennar
Contact: Site Public Contact
Phone: 877-467-3411
Merced
Mercy UC Davis Cancer Center
Contact: Site Public Contact
Phone: 209-564-3600
Email: ResearchInstituteInquiries@CommonSpirit.org
Napa
Providence Quuen of the Valley
Contact: Site Public Contact
Phone: 707-521-3830
Rocklin
Mercy Cancer Center - Rocklin
Contact: Site Public Contact
Phone: 916-556-3301
Email: OncologyResearch@DignityHealth.org
Sacramento
Mercy Cancer Center - Sacramento
Contact: Site Public Contact
Phone: 916-556-3301
Email: OncologyResearch@DignityHealth.org
San Luis Obispo
Pacific Central Coast Health Center-San Luis Obispo
Contact: Site Public Contact
Phone: 805-219-4673
Email: ResearchInstituteInquiries@CommonSpirit.org
Santa Maria
Mission Hope Medical Oncology - Santa Maria
Contact: Site Public Contact
Phone: 805-219-4673
Email: ResearchInstituteInquiries@CommonSpirit.org
Santa Rosa
Providence Santa Rosa Memorial Hospital
Contact: Site Public Contact
Phone: 707-521-3830
Providence Medical Foundation - Santa Rosa
Contact: Site Public Contact
Phone: 707-521-3830
Woodland
Woodland Memorial Hospital
Contact: Site Public Contact
Phone: 916-556-3301
Email: OncologyResearch@DignityHealth.org
Colorado
Aurora
UCHealth University of Colorado Hospital
Contact: Site Public Contact
Phone: 720-848-0650
Colorado Springs
Penrose-Saint Francis Healthcare
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Saint Francis Cancer Center
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Rocky Mountain Cancer Centers-Penrose
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Denver
Porter Adventist Hospital
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Durango
Southwest Oncology PC
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Mercy Medical Center
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Lakewood
Saint Anthony Hospital
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Littleton
Littleton Adventist Hospital
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Longmont
Longmont United Hospital
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Parker
Parker Adventist Hospital
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Pueblo
Saint Mary Corwin Medical Center
Contact: Site Public Contact
Phone: 719-776-6550
Email: ResearchTracking@Centura.Org
Connecticut
Derby
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Fairfield
Smilow Cancer Hospital Care Center-Fairfield
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Glastonbury
Smilow Cancer Hospital Care Center at Glastonbury
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Greenwich
Smilow Cancer Hospital Care Center at Greenwich
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Guilford
Smilow Cancer Hospital Care Center - Guilford
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
New Haven
Yale University
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Smilow Cancer Center/Yale-New Haven Hospital
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
North Haven
Yale-New Haven Hospital North Haven Medical Center
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Stamford
Smilow Cancer Hospital Care Center at Long Ridge
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Torrington
Smilow Cancer Hospital-Torrington Care Center
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Trumbull
Smilow Cancer Hospital Care Center-Trumbull
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Waterbury
Smilow Cancer Hospital-Waterbury Care Center
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Waterford
Smilow Cancer Hospital Care Center - Waterford
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Idaho
Boise
Saint Luke's Cancer Institute - Boise
Contact: Site Public Contact
Phone: 208-381-2774
Email: eslinget@slhs.org
Saint Alphonsus Cancer Care Center-Boise
Contact: Site Public Contact
Phone: 734-712-3671
Email: stephanie.couch@stjoeshealth.org
Caldwell
Saint Alphonsus Cancer Care Center-Caldwell
Contact: Site Public Contact
Phone: 734-712-3671
Email: stephanie.couch@stjoeshealth.org
Coeur D'Alene
Kootenai Health - Coeur d'Alene
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Emmett
Walter Knox Memorial Hospital
Contact: Site Public Contact
Phone: 734-712-3671
Email: stephanie.couch@stjoeshealth.org
Fruitland
Saint Luke's Cancer Institute - Fruitland
Contact: Site Public Contact
Phone: 208-381-2774
Email: eslinget@slhs.org
Meridian
Saint Luke's Cancer Institute - Meridian
Contact: Site Public Contact
Phone: 208-381-2774
Email: eslinget@slhs.org
Idaho Urologic Institute-Meridian
Contact: Site Public Contact
Phone: 734-712-3671
Email: stephanie.couch@stjoeshealth.org
Nampa
Saint Luke's Cancer Institute - Nampa
Contact: Site Public Contact
Phone: 208-381-2774
Email: eslinget@slhs.org
Saint Alphonsus Cancer Care Center-Nampa
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Post Falls
Kootenai Clinic Cancer Services - Post Falls
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Sandpoint
Kootenai Cancer Clinic
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Twin Falls
Saint Luke's Cancer Institute - Twin Falls
Contact: Site Public Contact
Phone: 208-381-2774
Email: eslinget@slhs.org
Illinois
Evanston
NorthShore University HealthSystem-Evanston Hospital
Contact: Site Public Contact
Phone: 847-570-2109
Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Contact: Site Public Contact
Phone: 847-570-2109
Highland Park
NorthShore University HealthSystem-Highland Park Hospital
Contact: Site Public Contact
Phone: 847-570-2109
Skokie
North Shore Medical Center
Contact: Site Public Contact
Phone: 888-823-5923
Email: ctsucontact@westat.com
Iowa
Ankeny
Mission Cancer and Blood - Ankeny
Contact: Site Public Contact
Phone: 515-282-2921
Clive
Mercy Cancer Center-West Lakes
Contact: Site Public Contact
Phone: 515-358-6613
Email: cancerresearch@mercydesmoines.org
Medical Oncology and Hematology Associates-West Des Moines
Contact: Site Public Contact
Phone: 515-241-3305
Council Bluffs
Alegent Health Mercy Hospital
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
Creston
Greater Regional Medical Center
Contact: Site Public Contact
Phone: 515-358-6613
Email: cancerresearch@mercydesmoines.org
Des Moines
Mercy Medical Center - Des Moines
Contact: Site Public Contact
Phone: 515-358-6613
Email: cancerresearch@mercydesmoines.org
Mission Cancer and Blood - Laurel
Contact: Site Public Contact
Phone: 515-241-3305
West Des Moines
Mercy Medical Center-West Lakes
Contact: Site Public Contact
Phone: 515-358-6613
Email: cancerresearch@mercydesmoines.org
Kentucky
Bardstown
Flaget Memorial Hospital
Contact: Site Public Contact
Phone: 859-629-7169
Email: ResearchInstituteInquiries@CommonSpirit.org
Corbin
Commonwealth Cancer Center-Corbin
Contact: Site Public Contact
Phone: 859-629-7169
Email: ResearchInstituteInquiries@CommonSpirit.org
Lexington
Saint Joseph Hospital
Contact: Site Public Contact
Email: protocols@swog.org
Saint Joseph Radiation Oncology Resource Center
Contact: Site Public Contact
Phone: 859-629-7169
Email: ResearchInstituteInquiries@CommonSpirit.org
Saint Joseph Hospital East
Contact: Site Public Contact
Phone: 859-629-7169
Email: ResearchInstituteInquiries@CommonSpirit.org
London
Saint Joseph London
Contact: Site Public Contact
Phone: 859-629-7169
Email: ResearchInstituteInquiries@CommonSpirit.org
Mount Sterling
Saint Joseph Mount Sterling
Contact: Site Public Contact
Email: protocols@swog.org
Louisiana
Metairie
LSU Healthcare Network / Metairie Multi-Specialty Clinic
Contact: Site Public Contact
Phone: 504-210-3539
Email: emede1@lsuhsc.edu
New Orleans
Louisiana State University Health Science Center
Contact: Site Public Contact
Phone: 504-210-3539
Email: emede1@lsuhsc.edu
Michigan
Ann Arbor
Saint Joseph Mercy Hospital
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Brighton
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Saint Joseph Mercy Brighton
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Canton
Trinity Health IHA Medical Group Hematology Oncology - Canton
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Saint Joseph Mercy Canton
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Caro
Caro Cancer Center
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Chelsea
Saint Joseph Mercy Chelsea
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Clarkston
Newland Medical Associates-Clarkston
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Hematology Oncology Consultants-Clarkston
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Detroit
Ascension Saint John Hospital
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
East China
Great Lakes Cancer Management Specialists-Doctors Park
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Flint
Genesee Hematology Oncology PC
Contact: Site Public Contact
Phone: 810-762-8038
Email: wstrong@ghci.org
Genesee Cancer and Blood Disease Treatment Center
Contact: Site Public Contact
Phone: 810-762-8038
Email: wstrong@ghci.org
Genesys Hurley Cancer Institute
Contact: Site Public Contact
Phone: 810-762-8038
Email: wstrong@ghci.org
Hurley Medical Center
Contact: Site Public Contact
Phone: 810-762-8038
Email: wstrong@ghci.org
Grosse Pointe Woods
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Academic Hematology Oncology Specialists
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Lansing
Sparrow Hospital
Contact: Site Public Contact
Phone: 517-364-9400
Livonia
Trinity Health Saint Mary Mercy Livonia Hospital
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Macomb Township
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Marlette
Saint Mary's Oncology/Hematology Associates of Marlette
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Pontiac
Saint Joseph Mercy Oakland
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Newland Medical Associates-Pontiac
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Hope Cancer Center
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
21st Century Oncology-Pontiac
Contact: Site Public Contact
Phone: 734-712-3671
Email: stephanie.couch@stjoeshealth.org
Saginaw
Ascension Saint Mary's Hospital
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Oncology Hematology Associates of Saginaw Valley PC
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Sterling Heights
Bhadresh Nayak MD PC-Sterling Heights
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Tawas City
Ascension Saint Joseph Hospital
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Warren
Macomb Hematology Oncology PC
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Advanced Breast Care Center PLLC
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Great Lakes Cancer Management Specialists-Macomb Professional Building
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Michigan Breast Specialists-Warren
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
Saint John Macomb-Oakland Hospital
Contact: Site Public Contact
Phone: 313-343-3166
Email: karen.forman@ascension.org
West Branch
Saint Mary's Oncology/Hematology Associates of West Branch
Contact: Site Public Contact
Phone: 989-907-8411
Email: lori.srebinski@ascension.org
Ypsilanti
Huron Gastroenterology PC
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Contact: Site Public Contact
Phone: 734-712-7251
Email: MCRCwebsitecontactform@stjoeshealth.org
Montana
Anaconda
Community Hospital of Anaconda
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Billings
Billings Clinic Cancer Center
Contact: Site Public Contact
Phone: 800-996-2663
Email: research@billingsclinic.org
Bozeman
Bozeman Deaconess Hospital
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Great Falls
Benefis Healthcare- Sletten Cancer Institute
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Great Falls Clinic
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Kalispell
Kalispell Regional Medical Center
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Missoula
Saint Patrick Hospital - Community Hospital
Contact: Site Public Contact
Phone: 406-327-3118
Email: amy.hanneman@providence.org
Community Medical Hospital
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Nebraska
Kearney
CHI Health Good Samaritan
Contact: Site Public Contact
Phone: 308-865-7963
Email: ResearchInstituteInquiries@CommonSpirit.org
Lincoln
Saint Elizabeth Regional Medical Center
Contact: Site Public Contact
Phone: 855-313-2409
Email: ResearchInstituteInquiries@CommonSpirit.org
Omaha
Alegent Health Immanuel Medical Center
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
Creighton University Medical Center
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
Alegent Health Lakeside Hospital
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
Alegent Health Bergan Mercy Medical Center
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
Papillion
Midlands Community Hospital
Contact: Site Public Contact
Phone: 402-717-1510
Email: ResearchInstituteInquiries@CommonSpirit.org
New York
Middletown
Garnet Health Medical Center
Contact: Site Public Contact
Phone: 845-333-1133
Email: jgerlach@garnethealth.org
Ohio
Cincinnati
TriHealth Cancer Institute-Anderson
Contact: Site Public Contact
Phone: 513-853-1300
Email: ResearchInstituteInquiries@CommonSpirit.org
TriHealth Cancer Institute-Westside
Contact: Site Public Contact
Phone: 513-853-1300
Email: ResearchInstituteInquiries@CommonSpirit.org
Good Samaritan Hospital - Cincinnati
Contact: Site Public Contact
Phone: 513-853-1300
Email: ResearchInstituteInquiries@CommonSpirit.org
Bethesda North Hospital
Contact: Site Public Contact
Phone: 513-853-1300
Email: ResearchInstituteInquiries@CommonSpirit.org
Oklahoma
Oklahoma City
University of Oklahoma Health Sciences Center
Contact: Site Public Contact
Phone: 405-271-8777
Email: ou-clinical-trials@ouhsc.edu
Oregon
Baker City
Saint Alphonsus Medical Center-Baker City
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Bend
Saint Charles Health System
Contact: Site Public Contact
Phone: 541-706-2909
Email: nosall@stcharleshealthcare.org
Clackamas
Clackamas Radiation Oncology Center
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Providence Cancer Institute Clackamas Clinic
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Coos Bay
Bay Area Hospital
Contact: Site Public Contact
Phone: 541-269-8392
Email: cherie.cox@bayareahospital.org
Newberg
Providence Newberg Medical Center
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Ontario
Saint Alphonsus Medical Center-Ontario
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Oregon City
Providence Willamette Falls Medical Center
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Portland
Providence Portland Medical Center
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Providence Saint Vincent Medical Center
Contact: Site Public Contact
Phone: 503-215-2614
Email: CanRsrchStudies@providence.org
Oregon Health and Science University
Contact: Site Public Contact
Phone: 503-494-1080
Email: trials@ohsu.edu
Redmond
Saint Charles Health System-Redmond
Contact: Site Public Contact
Phone: 541-706-2909
Pennsylvania
Allentown
Lehigh Valley Hospital-Cedar Crest
Contact: Site Public Contact
Phone: 610-402-9543
Email: Morgan_M.Horton@lvhn.org
Bethlehem
Lehigh Valley Hospital - Muhlenberg
Contact: Site Public Contact
Phone: 610-402-9543
Email: Morgan_M.Horton@lvhn.org
East Stroudsburg
Pocono Medical Center
Contact: Site Public Contact
Phone: 610-402-9543
Email: Morgan_M.Horton@lvhn.org
Hazleton
Lehigh Valley Hospital-Hazleton
Contact: Site Public Contact
Phone: 610-402-9543
Email: Morgan_M.Horton@lvhn.org
Rhode Island
Westerly
Smilow Cancer Hospital Care Center - Westerly
Contact: Site Public Contact
Phone: 203-785-5702
Email: canceranswers@yale.edu
Washington
Aberdeen
Providence Regional Cancer System-Aberdeen
Contact: Site Public Contact
Phone: 360-412-8958
Email: deidre.dillon@providence.org
Bellingham
PeaceHealth Saint Joseph Medical Center
Contact: Site Public Contact
Phone: 360-788-8223
Bremerton
Harrison Medical Center
Contact: Site Public Contact
Phone: 253-426-6882
Email: ResearchInstituteInquiries@CommonSpirit.org
Centralia
Providence Regional Cancer System-Centralia
Contact: Site Public Contact
Phone: 360-412-8958
Email: deidre.dillon@providence.org
Edmonds
Swedish Cancer Institute-Edmonds
Contact: Site Public Contact
Phone: 206-215-3086
Email: PCRC-NCORP@Swedish.org
Everett
Providence Regional Cancer Partnership
Contact: Site Public Contact
Phone: 425-261-3529
Email: marilyn.birchman@providence.org
Issaquah
Swedish Cancer Institute-Issaquah
Contact: Site Public Contact
Phone: 206-215-3086
Email: PCRC-NCORP@Swedish.org
Kennewick
Kadlec Clinic Hematology and Oncology
Contact: Site Public Contact
Phone: 509-783-4637
Email: research@kadlecmed.org
Lacey
Providence Regional Cancer System-Lacey
Contact: Site Public Contact
Phone: 360-412-8958
Email: deidre.dillon@providence.org
Longview
PeaceHealth Saint John Medical Center
Contact: Site Public Contact
Phone: 360-514-2016
Email: kmakin-bond@peacehealth.org
Seattle
Swedish Medical Center-First Hill
Contact: Site Public Contact
Phone: 206-215-3086
Email: PCRC-NCORP@Swedish.org
Swedish Medical Center-Ballard Campus
Contact: Site Public Contact
Phone: 206-215-3086
Email: PCRC-NCORP@Swedish.org
Swedish Medical Center-Cherry Hill
Contact: Site Public Contact
Phone: 206-215-3086
Email: PCRC-NCORP@Swedish.org
University of Washington Medical Center - Montlake
Contact: Site Public Contact
Phone: 800-804-8824
Fred Hutchinson Cancer Research Center
Contact: Site Public Contact
Phone: 800-804-8824
FHCC South Lake Union
Contact: Site Public Contact
Phone: 800-804-8824
Sedro-Woolley
PeaceHealth United General Medical Center
Contact: Site Public Contact
Phone: 360-788-8238
Email: lkey@peacehealth.org
Shelton
Providence Regional Cancer System-Shelton
Contact: Site Public Contact
Phone: 360-412-8958
Email: deidre.dillon@providence.org
Vancouver
PeaceHealth Southwest Medical Center
Contact: Site Public Contact
Phone: 360-514-3940
Email: kmakin-bond@peacehealth.org
Walla Walla
Providence Saint Mary Regional Cancer Center
Contact: Site Public Contact
Phone: 509-897-5993
Email: Cheryl.Dodd@providence.org
Yelm
Providence Regional Cancer System-Yelm
Contact: Site Public Contact
Phone: 360-412-8958
Email: deidre.dillon@providence.org
Wyoming
Cody
Billings Clinic-Cody
Contact: Site Public Contact
Phone: 800-996-2663
Email: research@billingsclinic.org
Sheridan
Welch Cancer Center
Contact: Site Public Contact
Phone: 406-969-6060
Email: mccinfo@mtcancer.org
Lead Researchers/Study PIs and Affiliation
Lead Organization SWOG
Principal Investigator Heather H. Cheng, MD PhD
This Study is Open To:
This study is open to people assigned male at birth who:
- have a diagnosis of prostate cancer.
- have a high or very high-risk prostate cancer defined by AT LEAST ONE of the following prior to registration:
- a minimum stage 3b prostate cancer, meaning the cancer extends beyond the prostate;
- Gleason Grade Group 4 or 5 (also known as Gleason sum 8-10); OR
- Prostate Specific Antigen, PSA, is a blood test ordered by your doctor
- have an inherited BRCA1 or BRCA2 mutation.
- had surgery or radiation for prostate cancer before registration.
This Study is Not Open To:
This study is not open to people who:
- will be treated for prostate cancer more thanone month into participating in this study.
- have been treated with radiation to the pelvic area.
- has metastatic cancer that is found through imaging less than 90 days before registration.
- people who have a tumor that can be removed by surgery can reach out to the study team to confirm if you are still eligible.
- do not have evidence of distant metastatic disease by conventional imaging within 90 days prior to registration.
- have initiated gonadotrophin releasing hormone (gnRH) agonist, gnRH antagonist, oral anti-androgen (e.g. bicalutamide, nilutamide, flutamide), or other drug intended to treat prostate cancer prior to registration. The effectiveness of the current depot of such treatment must not extend beyond 1 month after study registration. Agents listed above cannot be started after participant registration.
- are can undergo surgery and receive carboplatin.
About FORCE
FORCE is a national nonprofit organization, established in 1999. Our mission is to improve the lives of individuals and families affected by adult hereditary cancers.