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Education > XRAY > Hereditary Cancer Risk

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Hereditary Cancer Risk

71 through 80 of 135

Relevance: Medium-High

Strength of Science: Medium-High

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Study : Do Vitamin B supplements alter breast cancer risk for women with BRCA mutations?

Relevance: Medium-High

Strength of Science: Medium-High

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Most relevant for: High risk women with a BRCA1 or BRCA2 mutation

Vitamins are an essential part of our diet. Vitamin supplements are often used to improve general health. This study explores how vitamin B supplements may affect breast cancer risk in women with BRCA mutations. (5/17/19)

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Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : Gaps in information about breast cancer risk and prevention impact African American women

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: African American women who are at high risk for breast cancer

A study showed that African American women with increased breast cancer risk experienced greater burdens in obtaining information at each step compared to white women. Racial differences in preventive choices correlated with differences in information and provider access. (3/14/19)

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Prevalence of BRCA founder mutations in Bahamian women

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

Most relevant for: Bahamanian women

The Bahamas has the highest known frequency of BRCA mutations among people diagnosed with breast cancer. This study reviewed whether population-based BRCA testing (testing everyone regardless of family or personal history of cancer) would be an effective approach for finding mutation carriers in the Bahamas. (3/4/19)

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Relevance: Medium-Low

Strength of Science: Low

Research Timeline: Post Approval

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Study : Breast cancer implant study suggests links with illness but has serious flaws

Relevance: Medium-Low

Strength of Science: Low

Research Timeline: Post Approval

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Most relevant for: Women with or considering breast implant reconstruction

THIS INFORMATION HAS BEEN UPDATED: In October 2021, the FDA issued guidance for people with breast implants Read our latest review on this topic.  

An article in the Annals of Surgery, researchers conclude that their work supports an association between silicone breast implants and a range of conditions. This journal article was accompanied by two editorials in which experts voiced their disagreement with the way the analysis was performed and the conclusions of the authors. (2/21/19)

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Relevance: Medium-High

Study : FORCE online survey: What breast cancer information do young women want and where do they look for it?

Relevance: Medium-High

Most relevant for: Young women and the health care providers who treat them

FORCE developed the CDC-funded Examining Relevance of Articles to Young Survivors or XRAYS program to help young breast cancer survivors and those at high-risk better understand media coverage about new breast cancer research. To ensure that the program would be responsive to users’ needs, FORCE designed a web-based survey to assess where young women look for information about breast cancer and to learn their unmet information needs.  The results of this survey were published in the journal Health Communications. (1/18/19)

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Relevance: Medium-High

Strength of Science: Medium-High

Study : Breast cancer risk increases modestly after childbirth

Relevance: Medium-High

Strength of Science: Medium-High

Most relevant for: Women in their childbearing years

Does having children alter the risk of breast cancer? Women who give birth have a lower lifetime risk of breast cancer. However, newer data suggests that breast cancer risk increases immediately after childbirth. A study published in December 2018 examines data from the Premenopausal Breast Cancer Collective Group seeking to clarify this issue. (12/28/18)

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Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

Study : Inherited breast cancer in Nigerian women

Relevance: Medium-High

Strength of Science: High

Research Timeline: Post Approval

Most relevant for: Nigerian women or women of Nigerian descent who have breast cancer

A new study shows that among Nigerian women, one in eight cases of breast cancer is due to an inherited mutation in BRCA1, BRCA2, PALB2 or TP53. (12/5/18)

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Study : Can population-based DNA sequencing find more people at risk for hereditary cancers?

Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Most relevant for: Women over age 30

It is well documented that many BRCA mutation carriers are missed using current family history-based screening approaches. As a result, experts are beginning to call for population-based BRCA genetic testing—an organized effort to screen all women like we do for breast and cervical cancer.  A recent study looked at whether a population-based genetic testing approach would better identify mutation carriers compared with current practice. (11/17/18)

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Relevance: High

Quality of Writing: High

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Article : The importance of racial diversity in clinical trials

Relevance: High

Quality of Writing: High

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Most relevant for: People who are a member of a racial or ethnic minority group

This article by journalists Caroline Chen and Riley Wong looks at racial disparities between participation in clinical trials and the population of people with cancer. (11/6/18)

Este artículo está disponible en español.

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Relevance: Medium-Low

Strength of Science: Medium

Research Timeline: Human Research

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Study : A new method for determining whether genetic variants in BRCA1 increase cancer risk

Relevance: Medium-Low

Strength of Science: Medium

Research Timeline: Human Research

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Most relevant for: People who have a Variant of Uncertain Significance in a gene associated with cancer risk.

Ever since BRCA1 was discovered, researchers have been trying to understand which of the thousands of possible DNA changes in this gene increase cancer risk and which are harmless changes.  A new study in Nature reports how a cutting-edge technology called “genome editing” may be used to classify changes—known as variants of uncertain significance-in BRCA1 as harmful or harmless. Once validated, this same technology may be used to classify variants in other genes. (9/29/18)

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