Hereditary Cancer



Relevance: High
Most relevant for: People diagnosed with pancreatic cancer
Update: Genetic causes of hereditary pancreatic cancer: BRCA and beyond
An update on hereditary pancreatic cancer presented at the annual American Society of Clinical Oncology meeting covered genes and lifetime risk. The update emphasized that all pancreatic cancer patients should be offered genetic counseling and testing. Genetic test results may impact treatment, screening for other cancers and risk to family members. (11/26/19)
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Relevance: Medium-High
Most relevant for: People with early-stage breast cancer
Study: A new blood test may help predict early-stage breast cancer patients at highest risk for recurrence
Which patients are at risk for a relapse of early-stage breast cancer? Tests to predict recurrence would help find people who need more monitoring after treatment and provide a chance to find and treat them earlier. This study looked at whether a blood test for tumor DNA (called circulating tumor DNA or ctDNA) is useful for finding people with recurrence earlier than current clinical practice. (11/4/19)
Este artículo está disponible en español.
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Relevance: Medium-Low
Most relevant for: Women diagnosed with Ductal Carcinoma In Situ (DCIS)
Personal Story: A “flu shot” against breast cancer? Not so fast
There have been multiple reports in the media of a Florida woman who had a "shot" to treat her DCIS with a promising outcome. This XRAY reviews the underlying story about this early breast cancer vaccine trial. (10/25/19)
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Relevance: Medium-High
Most relevant for: Women with a family history of breast cancer
Study: Does eating meat affect breast cancer risk?
Eating meat has been suggested to increase breast cancer risk. The recent Sister Study looked at meat type, cooking methods and breast cancer risk in a study of 42,012 women. (9/10/19)
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Relevance: High
Most relevant for: People with a personal or family history of cancer where no mutation has been found
Study: MRI or mammograms for detecting breast cancer in families with unknown genetic mutations?
MRI and mammograms are used together to detect breast cancer in high-risk women who test positive for a BRCA or other gene mutation that increases the risk for breast cancer. For women with a family history of breast cancer but no known genetic mutation, increased screening is recommended. But what method is best? A recent clinical trial in the Netherlands compared MRI and mammography for this population. (8/15/19)
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Relevance: High
Most relevant for: Women with, or considering breast reconstruction with implants
Guideline: FDA asks Allergan to recall certain textured breast implants
On July 25, 2019, the Food and Drug Administration requested that breast implant manufacturer Allergan recall its BIOCELL textured implants and expanders due to an association with a rare type of lymphoma called Breast Implant Associated Anaplastic Large Cell Lymphoma or BIA-ALCL. The FDA does not recommend removing implants for people who do not have disease symptoms. This XRAYS review updates information about this FDA recall. (7/29/19)
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Relevance: Medium-High
Most relevant for: LGBTQ cancer patients and their healthcare providers.
Study: LGBTQ patients recommend improvements for their cancer care
Very little research has focused on the cancer care experiences of lesbian, gay, bisexual, transgender and queer (LGBTQ) people. This study looks at recommendations from the LGBTQ community for improving their cancer care. (6/20/19)
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Relevance: Medium-High
Most relevant for: Young women of color with a BRCA mutation
Personal Story: A young woman's story of genetic testing and risk-reducing mastectomy
Alejandra Campoverdi comes from a family with three generations of breast cancer. As a former White House aide and active educator in the Latina community, she has openly shared her story of genetic testing, her BRCA2 mutation and her plans for risk-reducing mastectomy at age 39. (6/6/19)
Este artículo está disponible en español.
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Relevance: Medium-High
Most relevant for: High risk women with a BRCA1 or BRCA2 mutation
Study: Do Vitamin B supplements alter breast cancer risk for women with BRCA mutations?
Vitamins are an essential part of our diet. Vitamin supplements are often used to improve general health. This study explores how vitamin B supplements may affect breast cancer risk in women with BRCA mutations. (5/17/19)
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Relevance: High
Most relevant for: African American women who are at high risk for breast cancer
Study: Gaps in information about breast cancer risk and prevention impact African American women
A study showed that African American women with increased breast cancer risk experienced greater burdens in obtaining information at each step compared to white women. Racial differences in preventive choices correlated with differences in information and provider access. (3/14/19)
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