BARD1 Gene Mutations
Information for People with an Inherited BARD1 Mutation
What are the cancer risks for people with a mutation?
Mutations in the gene have been linked to increased risk for breast cancer in women. Currently, it is not believed that mutations increase the risk for other cancers, but research on this is continuing.
What can people with a mutation do?
There are guidelines for breast cancer screening for women with a mutation.
People with a mutation who have been diagnosed with some types of cancer may qualify for specific treatments or clinical trials using targeted therapies.
Each of these topics is outlined in more detail in the sections highlighted below.
More Information on Mutations
Cancer Risks
Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for cancer in people with inherited BARD1 mutations.
Risk Management Options
Read about the latest expert guidelines for cancer screening and prevention for people with a BARD1 mutation.
Cancer Treatment Options
People who test positive for a BARD1 mutation may have additional treatment or clinical trial options available to them.
Participate in Treatment Research
The treatment studies below are enrolling people with mutations. To search for more studies, visit our Search and Enroll Tool.
Clinicaltrials.gov identifier: NCT04038502
New Treatment in People with Triple Negative Breast Cancer or Advanced Solid Tumors
Clinicaltrials.gov identifier: NCT06022029
