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BARD1 Gene Mutations

Learn about the cancer risks, screening, prevention and treatment options for people with inherited BARD1 mutations. Stay up to date by signing up for our community newsletter.
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Information about Inherited BARD1 Mutations

What is BARD1?

BARD1 is a gene that helps repair damage to your DNA. People who are born with changes—called mutations—in their BARD1 gene have an increased risk for cancer.   

What are the cancer risks for people with a BARD1 mutation?

Mutations in the BARD1 gene have been linked to increased risk for breast cancer in women. Currently, it is not believed that BARD1 mutations increase the risk for other cancers, but research on this is continuing.

What can people with a BARD1 mutation do?

There are guidelines based on the latest research for breast cancer risk management in  women with a BARD1 mutation. 

People with a BARD1 mutation who have been diagnosed with some types of cancer may qualify for specific treatments or clinical trials using targeted therapies. 

If you test positive for a BARD1 mutation, you should inform your close blood relatives (first-, second-, and third-degree relatives) about your test results and encourage them to speak with a genetics expert. 

Each of these topics is outlined in more detail in the sections highlighted below. 

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More Information for people with BARD1 Mutations

Cancer Risks

Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for cancer in people with inherited BARD1 mutations. 

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Risk Management Options

Read about the latest expert guidelines for cancer screening and prevention for people with a BARD1 mutation. 

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Cancer Treatment Options

People who test positive for a BARD1 mutation may have additional treatment or clinical trial options available to them. 

More info

Last updated March 07, 2025