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Endometrial Cancer Treatment

Learn about national guidelines and treatment options for people with hereditary endometrial cancer.

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Endometrial Cancer > Treatment Options

Endometrial Cancer Treatment

Treatment for endometrial cancer depends on the stage and type of the disease based on pathology results. Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer. For people with metastatic or advanced cancer, these additional tests are usually recommended.

Standard treatment may include a combination of surgery, chemotherapy, radiation and hormone therapy. Some people may also benefit from treatment with immunotherapies or targeted therapies. Clinical trials may be available for any stage of cancer.

Which genes are linked to hereditary endometrial cancer?

About 10 percent of people diagnosed with endometrial cancer will test positive for an inherited mutation. People with an inherited mutation in the genes below may have different treatment recommendations or options. 

Genes Linked to Endometrial Cancer

*BRCA1 and and BRCA2 mutations have been linked to a rare type of endometrial cancer known as uterine serous carcinoma.

Make sure that you receive a copy of your cancer test results, including your pathology report and your cancer stage. Ask your doctor to explain your diagnosis, test results and treatment options in terms that you can understand. This will allow you to work with your doctor to choose the treatment plan that is right for you.   

See below for more information on each of these endometrial cancer treatment topics. 

In the News

Immunotherapy improves outcomes of advanced endometrial cancer

Study : Immunotherapy improves outcomes of advanced endometrial cancer

Standard treatment for advanced endometrial cancer may soon change. A study found that people with advanced or recurrent endometrial cancer who received immunotherapy with chemotherapy had better outcomes than those who had chemotherapy alone. (Posted...

More Information on Endometrial Cancer Treatment

Stages & Subtypes

Treatment for endometrial cancer depends on the stage and type based on pathology results. Learn how doctors determine the stage and subtype of endometrial cancers.

More info

Standard Therapies

Treatment for endometrial cancer often includes a combination of surgery, chemotherapy, radiation and hormone therapy. Learn more about these types of treatments.

More info

Biomarker Testing

Tumor biomarker testing and genetic testing can provide additional clues about which treatments may work best against your cancer.

More info

Targeted & Immunotherapies

Targeted therapies are designed to attack or kill cancer cells, while sparing normal cells as much as possible. Immunotherapies help the body’s immune system detect and attack cancer cells. 

More info

Genetic Testing for Inherited Mutations

There are national guidelines that outline who should consider genetic counseling and testing for an inherited mutation linked to cancer. 

More info


Last updated July 14, 2024