HOXB13 Gene Mutations
Information for People with an Inherited Mutation
What are the cancer risks for people with a mutation?
Mutations in the have been linked with an increased risk for cancer. There is not enough research to conclude that a mutation increases the risk of other cancers.
What can people with a mutation do?
There are guidelines for cancer screening for people with mutations.
People with an inherited mutation who have been diagnosed with cancer may qualify for specific treatments or clinical trials.
Each of these topics is outlined in more detail in the sections highlighted below.
More Information on Mutations
Cancer Risks
Cancer risk estimates are updated based on the latest research. Read about the lifetime risk for cancer in people with inherited mutations.
Risk Management Options
Read about the latest expert guidelines for cancer screening and prevention for people with a mutation.
Cancer Treatment Options
People who test positive for a mutation may have additional treatment or clinical trial options available to them.
Participate in Research
The cancer screening and prevention studies below are enrolling people with mutations. To search for more studies, visit our Search and Enroll Tool.
Screening Study for Men at High Genetic Risk for Prostate Cancer
Clinicaltrials.gov identifier:
NCT03805919
Prostate Cancer Genetic Risk Evaluation and Screening Study (PROGRESS)
Clinicaltrials.gov identifier:
NCT05129605
Screening in Men at High Risk of Developing Prostate Cancer
Clinicaltrials.gov identifier:
NCT05608694