Get notified of page updates

Signs of an Inherited Mutation

Are you concerned that the cancer in your family is hereditary. Learn about the signs of an inherited gene mutation linked to cancer.

Stay up to date on research and information

Sign Up for FORCE Newsletters

Hereditary Cancer and Genetic Testing > Hereditary Cancer > Signs of an Inherited Mutation

Glossary on
off

Signs of an Linked to Cancer Risk 

If you or a relative have been diagnosed with cancer, it may be due to an . Signs of an or  include the following:

You have a blood relative who has tested positive for an inherited gene mutation linked to cancer.

OR

You or any of your family members have had:

  • Pancreatic, ovarian, , primary peritoneal or male breast cancer at any age.
  • Breast, colorectal or endometrial cancer at age 50 or younger.
  • Two separate cancer diagnoses.
  • A type of breast cancer called “” at any age.
  • cancer at age 55 or younger or   cancer.
  • Colorectal cancer at any age with tumor testing that shows  () or other tumor test results that are suggestive of .
  • Endometrial cancer at any age with tumor testing that shows  () or other tumor test results that are suggestive of .
  • More than 10 colon .
  • Rare or young-onset cancers.
  • Tumor testing that shows a mutation in a gene associated with .
  • Eastern European Jewish ancestry and breast, ovarian or pancreatic cancer at any age.

OR

More than one family member on the same side of your family has had a combination of the following cancers:

  • Breast cancer
  • Ovarian, or primary peritoneal cancer
  • cancer
  • Pancreatic cancer
  • Melanoma
  • Colorectal cancer
  • Endometrial cancer
  • Stomach cancer
  • Rare or young-onset cancers

This is not a complete list; other cancers may be hereditary too. If you would like to learn if the cancer in your family is hereditary, it is important to speak with a genetics expert.

Last updated August 11, 2024