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Breast Cancer: Early Detection

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Screening for Breast Cancer

This section covers the following topics:

 


Note that when we use the terms "male" and "men" we are referring to people assigned male at birth. When we use the terms "female" and "women" we are referring to people assigned female at birth. 


Types of breast screening

Screening for breast cancer uses tests to try to catch cancer in its early stages, when it is most treatable. The earlier that cancer is found, the better a person’s chance of surviving it. The most common types of breast screening include:

 

Breast exams, breast awareness and breast cancer symptoms

Breast exams involve feeling the breast tissue for lumps or other changes that might be cancer.

  • During a clinical breast exam () the doctor or nurse carefully feels the entire breast to find lumps or other abnormal changes.
  • A breast self exam () involves a person checking their own breasts on a monthly basis to look for abnormalities. is no longer recommended for women by some organizations, but others continue to recommend since many cancers are initially found this way. Experts recommend training high risk men to perform .  
  • Breast awareness is a term that highlights the importance of people knowing what normal breast tissue should feel like and reporting any changes or abnormalities in their breasts to their doctors. Similar to a breast self exam, breast awareness requires people to check their breasts at regular intervals. Ask your doctor to explain what you should look for and when to report changes. 
  • Some of the symptoms of breast cancer are listed below. Importantly, these symptoms do not mean you definitely have cancer. Also, many breast cancers don't cause any symptoms. Report any of the following to your doctor:
    • a lump or abnormal mass in the the breast
    • breast swelling 
    • dimpling or puckering of the skin of the breast
    • changes in the nipple (turning inward, red, thickened, dry and flaking
    • nipple discharge (other than milk)
    • swelling of the in the armpits or collar bone area

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use xrays to look at the breast tissue. , like other xrays, expose people to a small amount of radiation. They are considered safe for most women, however experts recommend that women who may be sensitive to radiation should avoid and use breast MRIs instead. This group includes women under the age of 30 and women with certain inherited mutations, such as is the most commonly used screening tool to detect breast cancer. find cancers in women of all ages, however, are less effective for women with dense breast tissue. You can read more about breast density and how it's measured and reported in the article on the right. For women with dense breasts, or may find cancers that were not seen with .


3D

Breast , also known as 3-D , uses xrays to take a series of images that give a layer-by-layer, 3-dimensional picture of the breast. Because of this, 3D  may find cancers earlier than traditional . They are also less likely to give a "" result, when a person is called back for an abnormality that turns out to be cancer. The radiation exposure  from  is small, and does not increase the risk for breast cancer.


Breast

Breast Magnetic Resonance Imaging () is an imaging method that uses magnetic fields rather than xrays to produce a detailed picture of the breasts.  is sensitive and may pick up an abnormality not seen by other imaging tools. For this reason, is recommended for women at high risk for breast cancer. There is also a greater chance for  to find changes that need a biopsy, but end up being benign (not cancer). These are known as "" results. 

exams that look for cancer require the injection of a contrast agent called gadolinium. The contrast helps doctors spot breast abnormalities more easily. There is some concern that with repeated use during yearly breast screenings, gadolinium could build up in the brain. Researchers are studying whether this buildup is harmful to some people. At the moment, most experts have concluded that the benefit of using contrast agents for breast MRIs in high risk women outweighs the small possible risks. Newer agents are available that may cause less buildup in the brain. It is important that you talk with your doctor about the risks and benefits of annual with gadolinium contrast. 


uses sound waves to image the breast. may be used to find cancers in women with dense breasts, which can hide cancer on a . is painless, ses no radiation and is widely available.  is less sensitive than breast and therefore is not usually used for screening high risk women who already receive yearly MRIs.  

In the News

 

What is breast density and why does it matter?

Guideline : What is breast density and why does it matter?

New FDA guidelines for mammograms will go into effect by September 2024. Current FDA guidance requires hospitals and breast centers to give people information about...

Yearly breast MRI screening improves outcomes for women with inherited BRCA mutations

Study : Yearly breast MRI screening improves outcomes for women with inherited BRCA mutations

An international research study of yearly breast MRI screening among women with BRCA1 and BRCA2 gene mutations found that BRCA1 carriers who had MRI screenings...


Breast screening guidelines

Experts have different recommendations for screening based on a person's risk for breast cancer. Breast cancer screening guidelines are different for people at high risk and average risk. Note that when we use the term "men" and "males," we are referring to people assigned male at birth. Note that when we use the term "women" and "females," we are referring to people assigned female at birth. 

Screening for high-risk women

The National Comprehensive Cancer Network (NCCN), is an organization of cancer experts that creates guidelines on cancer care and updates them yearly. They create separate guidelines for women at increased risk for breast cancer due to inherited mutations or other risk factors. Screening guidelines for high risk women usually includes a combination of breast exams, 3D and breast MRIs, often beginning at age 25. You can find information on screening guidelines for specific gene mutations linked to breast cancer here

Screening

Beginning Age

Breast awareness

  • Learn how to examine your breasts, be aware of and report any changes to your doctor.

Age to begin depends on the gene:

  • 18: BRCA1, BRCA2, PTEN, TP53
  • 25: ATM, BARD1, CDH1, CHEK2, NF1, PALB2, RAD51C, RAD51D, STK11

Clinical breast exam

  • Examination by doctor every 6-12 months.

Age to begin depends on the gene:

  • 18: BRCA1, BRCA2, PTEN, TP53
  • 25: ATM, BARD1, CDH1, CHEK2, NF1, PALB2, RAD51C, RAD51D, STK11

Breast MRI

  • Recommendation depends on the gene.
  • For some genes, the guidelines say to "consider MRI." This means have a conversation with your healthcare team on the benefits, costs and risks and making a decision.
    • ATM, BARD1, CDH1, CHEK2, NF1, RAD51C, RAD51D
  • For the following genes, the guidelines say "recommend." For those genes, experts believe the benefits outweight the costs and risks.
    • BRCA1, BRCA2, PALB2, PTEN, STK11, TP53

    Age to begin depends on the gene and family history (for families with members who had breast cancers diagnosed before the recommended screening age, screening may begin earlier):

    • 20: TP53
    • 25: BRCA1, BRCA2
    • 30 - 35: ATM, CDH1, CHEK2, NF1, PALB2, PTEN, STK11
    • 40: BARD1, RAD51C, RAD51D

    Mammogram

      Age to begin depends on the gene and family history (for families with members who had breast cancers diagnosed before the recommended screening age, screening may begin earlier):

      • 30: BRCA1, BRCA2, CDH1, NF1, PALB2, PTEN, STK11, TP53
      • 40: ATM, BARD1, CDH1, CHEK2, RAD51C, RAD51D

      Source: NCCN Guidelines: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, v1. 3 2025


      Screening for high-risk men

      NCCN recommends the following screening for men with an linked to breast cancer. Individual recommendations may vary by gene mutation.

      Recommendation

      Beginning Age

      Learn how to do a breast self-exam and be aware of changes in your breasts.

      35

      Breast exam by doctor every 6-12 months.

      35

      Have a discussion with your doctor about the benefits, risks and costs of annual mammograms.

      50 (or earlier based on the youngest case of male breast cancer in the family)

      Source: NCCN Guidelines: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, vs. 1 2025


      Paying for high-risk screening

      The federal Affordable Care Act requires most health insurance companies to pay for annual for women 40 and older with no out-of-pocket costs. High-risk women are recommended to have additional breast screenings such as , starting at a younger age. Many states have laws requiring coverage of these “supplemental” screenings and other health services for individuals at increased risk of cancer. Visit our page on on high-risk breast screening coverage. 

      Despite federal and , some health plans still deny coverage for high-risk screening or charge large out-of-pocket fees. You can file an appeal with your health plan. Visit our page with tips for filing an appeal and our page with sample appeal letters. 

      For people with or without insurance who cannot afford high risk screening, the 's National Breast and Cervical Cancer Early Detection Program provides each state with funding for low-cost breast screening. For some states, but not all, this includes funding for breast for people who meet the guidelines. Visit their page for more information about low-cost screening in your state. 

      Federal laws and most do not cover breast screening for high-risk men. This means that high-risk men may need to pay out-of-pocket costs for high-risk screening. 


      Screening for average-risk women

      Several organizations publish different breast screening guidelines for average-risk women. Not all of these guidelines are the same, which can lead to confusion.

      Organization

      Age to Start / Type of Screening

      Additional Notes

      National Comprehensive Cancer Network (NCCN)

      Age 25:

      • practice breast awareness
      • clinical breast exam every 1-3 years

      Age 40:

      • yearly mammogram - consider 3D mammogram if available
      • discuss benefits, risks and costs of additional screening (for example MRI) for women with dense breasts

      Starting at age 25, women should speak with their doctors about their risk of breast cancer. Breast cancer risk assessment includes discussion about family history of cancer and other risks factors.

      American Cancer Society

      Age 40

      • Discuss the benefits, risks and costs of beginning annual mammograms at age 40

      Ages 45 - 54

      • Mammogram yearly

      Ages 55 - and older

      • Mammogram every other year or yearly based on patient's preference

      Screening should continue as long as a woman is in good health and is expected to live at least 10 more years.

      United States Preventive Services Task Force

      Age 40

      • Mammograms every 2 years

      Screening should continue until age 75.


      When an abnormality is found

      If a breast lump is felt on exam, doctors will usually order diagnostic testing to see if the lump is cancer. This may include , , (a test that uses sound waves to look more closely at breast tissue) and a biopsy. Abnormalities found on or may require additional imaging or a biopsy. 


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      Last updated September 27, 2024