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Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

High-risk localized prostate cancer
Clinicaltrials.gov identifier:NCT04030559
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About the Study
NOTE: This study is no longer recruiting people.
This study will look at how well the niraparib works, when given before a radical prostatectomy, for people with high-risk cancer that has not spread to other parts of the body, and who have a tumor mutation in any of the following genes:BRCA1/2, , CDK12, CHEK1/2 FANCA, FANCD2, FANCL, GEN1, , , RAD51, , and .
This Study is Open To:
NOTE: This study is no longer recruiting people.
This Study is NOT Open To:
NOTE: This study is no longer recruiting people.
High-risk localized prostate cancer
Clinicaltrials.gov identifier:NCT04030559