Treatment
Biomarker study for people with early-stage breast cancer
Clinicaltrials.gov identifier:NCT06401421
Study Contact Information:
For more information please contact:
NSABP Department of Site and Study Management Department of Site and Study Management
Phone: 1-800-270-3165
Email: industry.trials@nsabp.org
Looking at Tumor DNA Before Chemotherapy to Predict Cancer Recurrence in People with High-Risk, Early-Stage Breast Cancer
Treatment
Biomarker study for people with early-stage breast cancer
Clinicaltrials.gov identifier:NCT06401421
Study Contact Information:
For more information please contact:
NSABP Department of Site and Study Management Department of Site and Study Management
Phone: 1-800-270-3165
Email: industry.trials@nsabp.org
This trial is looking at whether the study of a type of called circulating tumor () can predict the likelihood of recurrence for people with breast cancer. The test is a blood test that looks for small pieces from cancer cells in the bloodstream.
This Study is Open To:
People who are 18 years or older can participate if they meet all of the following criteria:
- Diagnosed with breast cancer.
- Are planning to receive chemotherapy before surgery ( chemotherapy).
- Have a tumor size of 2.1 cm or larger.
- Have one of the following:
- spread to (lymph node positive), or
- Triple-negative or HER2+, or
- HR-positive/HER2-negative with at least one of the following:
- high grade tumor
- high Ki67 index of 20% or higher (Ki67 scale is often used in a cancer diagnosis to assess how quickly a tumor is growing).
- High genomic risk score (measurement of an individual’s predisposition to breast cancer).
- They agree to provide blood for each research blood draw.
- They are able to provide a tissue sample from a previous breast biopsy or a lymph node.
This Study is NOT Open To:
People with the following are not eligible to participate:
- Have cancer.
- Have already started treatment to try to shrink the breast cancer tumor.
- Completed treatment less than 5 years ago for a previously-diagnosed cancer.
- Have two or more separate breast tumors in the same or opposite breast.
Blood and tissue samples will be collected for the test.
- Participants will provide 34 cc (2.5 Tablespoons) of blood for each research blood draw.
- Participants will provide a tissue sample from a breast biopsy or a lymph node.
Patient outcomes will be monitored for six years.
Study Contact Information:
For more information please contact:
NSABP Department of Site and Study Management Department of Site and Study Management
Phone: 1-800-270-3165
Email: industry.trials@nsabp.org
Locations:
Alaska
City: Anchorage RECRUITING
Facility: Katmai Oncology Group - Anchorage
Contact Info:
California
City: Palo Alto RECRUITING
Facility: Stanford Cancer Institute
Contact Info:
City: Vallejo RECRUITING
Facility: Kaiser Permanente Medical Center
Contact Info:
Florida
City: Altamonte Springs RECRUITING
Facility: AdventHealth East Altamonte Oncology and Hematology
Contact Info:
City: Miami Beach RECRUITING
Facility: Mount Sinai Medical - Comprehensive Cancer Center
Contact Info:
City: Plantation RECRUITING
Facility: Baptist Cancer Care - Plantation
Contact Info:
City: Tampa RECRUITING
Facility: St. Joseph's Women's Hospital
Contact Info:
Illinois
City: Chicago RECRUITING
Facility: Rush Cancer Center
Contact Info:
Kentucky
City: Edgewood RECRUITING
Facility: St. Elizabeth Edgewood Hospital
Contact Info:
City: Louisville RECRUITING
Facility: Norton Cancer Institute - Downtown
Contact Info:
City: Louisville RECRUITING
Facility: Baptist Health Louisville
Contact Info:
Massachusetts
City: Burlington RECRUITING
Facility: Lahey Hospital & Medical Center
Contact Info:
Maryland
City: Baltimore RECRUITING
Facility: Greater Baltimore Medical Center
Contact Info:
City: Baltimore RECRUITING
Facility: Sinai Hospital of Baltimore
Contact Info:
City: Baltimore RECRUITING
Facility: MedStar Georgetown Cancer Institute
Contact Info:
City: Bethesda RECRUITING
Facility: The Center for Cancer and Blood Disorders - Bethesda
Contact Info:
City: Glen Burnie RECRUITING
Facility: Tate Cancer Center at UM Baltimore Washington
Contact Info:
City: Silver Spring RECRUITING
Facility: Holy Cross Hospital - Silver Spring
Contact Info:
City: Towson RECRUITING
Facility: University of Maryland St. Joseph Medical Center
Contact Info:
Minnesota
City: Saint Louis Park RECRUITING
Facility: Metro Minnesota Community Oncology Consortium (MMCORC)
Contact Info:
North Carolina
City: Charlotte RECRUITING
Facility: Atrium Health Levine Cancer Institute
Contact Info:
City: Pinehurst RECRUITING
Facility: FirstHealth Outpatient Cancer Center
Contact Info:
City: Rocky Mount RECRUITING
Facility: UNC Cancer Care at Nash
Contact Info:
New Jersey
City: New Brunswick RECRUITING
Facility: Rutgers Cancer Institute of New Jersey
Contact Info:
New York
City: Stony Brook RECRUITING
Facility: Stony Brook Medicine
Contact Info:
Ohio
City: Canton RECRUITING
Facility: Aultman Timken Family Cancer Center
Contact Info:
City: Cleveland RECRUITING
Facility: Cleveland Clinic Main Campus
Contact Info:
Pennsylvania
City: Harrisburg RECRUITING
Facility: Penn State Health Medical Group - Andrews Patel
Contact Info:
City: Hershey RECRUITING
Facility: Penn State Cancer Institute
Contact Info:
City: Pittsburgh RECRUITING
Facility: UPMC Magee - Womens Hospital
Contact Info:
Rhode Island
City: Providence RECRUITING
Facility: Women & Infants Hospital
Contact Info:
South Dakota
City: Sioux Falls RECRUITING
Facility: Avera Cancer Institute
Contact Info:
Tennessee
City: Kingsport RECRUITING
Facility: Ballad Health Cancer Center
Contact Info:
Texas
City: Houston RECRUITING
Facility: The University of Texas MD Anderson Cancer Center
Contact Info:
City: Lubbock RECRUITING
Facility: Joe Arrington Cancer Research & Treatment Center
Contact Info:
Virginia
City: Midlothian RECRUITING
Facility: Bon Secours Cancer Institute at St. Francis
Contact Info:
City: Richmond RECRUITING
Facility: VCU Massey Comprehensive Cancer Center
Contact Info:
Wisconsin
City: Wauwatosa RECRUITING
Facility: Aurora Cancer Care - Wauwatosa
Contact Info:
West Virginia
City: Morgantown RECRUITING
Facility: WVU Cancer Institute
Contact Info:
Other Countries
Country: Canada
State: Quebec
City: Montréal RECRUITING
Facility: Maisonneuve-Rosemont Hospital (HMR)
Contact Info:
Country: Canada
State: Quebec
City: Montréal RECRUITING
Facility: Centre Hospitalier de l'Université de Montréal (CHUM)
Contact Info:
Country: Canada
State: Quebec
City: Montréal RECRUITING
Facility: Jewish General Hospital
Contact Info:
Country: Canada
State: Quebec
City: Montréal RECRUITING
Facility: McGill University Health - Glen Site
Contact Info:
Country: Canada
State: Quebec
City: Québec City RECRUITING
Facility: Hôpital du Saint-Sacrement
Contact Info: