Hereditary Cancer

12 May 2025

Study : Impact of mental healthcare among those with increased pancreatic cancer risk

Most relevant for: People with hereditary pancreatic cancer risk or strong family history of pancreatic cancer

Pancreatic cancer is often aggressive and diagnosed at a late stage, which can lead to uncertainty and fear. For those at risk due to a genetic mutation or family history, access to surveillance and mental health support is essential to help manage the emotional impact.  (Posted 5/12/25)

23 April 2025

Study : Hereditary cancer mutations among people with multiple myeloma

Most relevant for: People with multiple myeloma or who have families with multiple myeloma

People with multiple myeloma who have inherited gene mutations are more likely to have had another cancer previously and may respond better to certain treatments than people with multiple myeloma who do not have inherited mutations. Individuals with an inherited BRCA1 and BRCA2 mutation may have a slightly increased risk for multiple myeloma, but more research is needed to confirm this. (Posted 4/23/25)

28 February 2025

Topic : Addressing the needs of young adults with breast cancer

Most relevant for: Young women with breast cancer concerned about survivorship issues

This update addresses common concerns faced by young adults with breast cancer, particularly fertility and childbearing, psychosocial health and treatment-related side effects. (Posted 2/28/25)

Este artículo está disponible en español.

13 February 2025

Study : Impact on sexual well-being among people with an inherited BRCA mutation

Most relevant for: People with an inherited mutation that increases cancer risk who are interested in sexual health

This study looked at sexual well-being in those with an inherited BRCA1 or BRCA2 mutation. Knowledge about having an inherited BRCA1 or BRCA1 mutation did not influence sexual health. However, menopause and cancer diagnosis was had a significant impact on sexual health and sexual function. (Posted 2/13/25)

Este artículo está disponible en español.

23 January 2025

Study : Risk of peritoneal cancer is low for people with an inherited BRCA mutation after surgery

Most relevant for: People with a BRCA1 or BRCA2 mutation who have had risk-reducing surgery to remove their ovaries

The risk of peritoneal cancer is low in people with an inherited BRCA1 or BRCA2 mutation after risk-reducing ovary removal (oophorectomy). The risk was even lower when risk-reducing surgery was done at a young age and after 2005 when removal of the fallopian tubes was included in the procedure. The findings of this research support the theory that like ovarian cancer, peritoneal cancer begins in the fallopian tubes and reinforces the age recommendation for surgery. (Posted 1/23/25)

Este artículo está disponible en español.

6 January 2025

Guideline : Hereditary cancer gene guidelines expand

Most relevant for: People at high risk for hereditary cancer

The National Comprehensive Cancer Network regularly updates guidelines for several types of hereditary cancer. These recommendations often change when new research is published. Recently, the NCCN expanded its guidelines to include information on hereditary prostate and gastric cancers. (Posted 1/6/25)

Este artículo está disponible en español.

10 December 2024

Study : Lifetime cancer risks in people with an inherited mutation in CDH1

Most relevant for: People with an inherited mutation in CDH1

This study looked at the lifetime risks of stomach and breast cancer in families with a known CDH1 mutation. Results from the study suggest that for some CDH1 mutation carriers lifetime stomach cancer risk is lower than previous research has shown. Additionally, study results show that the lifetime risk of breast cancer is similar to previous lifetime risk estimates in women with mutations in this gene. (Posted 12/10/24)

Este artículo está disponible en español.

22 November 2024

Article : Life with a high-risk pancreatic and melanoma cancer mutation

Most relevant for: People with an inherited mutation in CDKN2A

One woman seeks genetic testing after her sister died of pancreatic cancer. Despite how her family’s mutation in the CDKN2A gene resulted in multiple cancer diagnoses and deaths and a suspicious finding during her own pancreatic cancer screening, Amarensia Spruitenburg shares a message of hope and gratitude. By telling her story, Amarensia highlights the impact that hereditary cancer can have on families.  (Posted 11/22/24)

Este artículo está disponible en español.

31 October 2024

Study : Impact of breast cancer and BRCA mutations on fertility preservation

Most relevant for: People considering fertility preservation.

Timely family planning discussions are important for people diagnosed with breast cancer as well as those who have an inherited a BRCA1 or BRCA2 mutation. This study looked at the number of mature eggs recovered when ovaries were stimulated for fertility preservation or preimplantation genetic testing among three groups and found that the number of eggs collected was similar. (Posted 10/31/24)

Este artículo está disponible en español.

8 October 2024

Study : More research points to the benefits of pancreatic cancer screening

Most relevant for: People undergoing pancreatic cancer screening

People with a family history of pancreatic cancer or those who have an inherited mutation that increases risk may benefit from yearly pancreatic cancer screening. Yearly screening may lead to early diagnosis and longer survival. (Posted 10/8/24)

Este artículo está disponible en español.