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Education > XRAY > Metastatic Breast Cancer

FORCE's eXamining the Relevance of Articles for You (XRAY) program looks behind the headlines of cancer news to help you understand what the research means for you. XRAY is a reliable source of hereditary cancer research-related news and information.
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Metastatic Breast Cancer

31 through 40 of 113

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : Genetic testing for inherited mutations may be helpful for all people with advanced or metastatic cancer

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: people with metastatic or recurrent cancer

In a study of nearly 12,000 cancer patients with a variety of cancers, eight percent of participants with metastatic cancer had an inherited mutation in a cancer gene that qualified them for a targeted treatment approved by the FDA or for participation in a clinical trial. The majority of people with metastatic cancer were unaware that they had an inherited mutation, and had not receive gene-directed treatment to which their tumor may have responded. The study authors suggest that genetic testing for inherited mutations may be warranted for all patients with advanced or metastatic cancer. (posted 9/30/21)

Este artículo está disponible en español.

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Relevance: Medium-Low

Research Timeline: Human Research

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Update : Blood tests called liquid biopsies for cancer screening, monitoring and treatment

Relevance: Medium-Low

Research Timeline: Human Research

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Most relevant for: People considering a liquid biopsy to screen for cancer

Could a simple blood test change cancer detection, treatment and monitoring? Several companies are offering a type of blood test known as a liquid biopsy to detect multiple cancers at their earliest stages, monitor response to treatment and help choose the best treatment. Although progress has been made using liquid biopsies to treat cancer, these tests have not yet been shown to detect cancer early enough to save lives. (posted 9/29/21)

Este artículo está disponible en español.

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Relevance: Medium-High

Quality of Writing: High

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Article : Transgender peoples' perspectives of being diagnosed with gender-associated cancer

Relevance: Medium-High

Quality of Writing: High

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Most relevant for: transgender people

An ABC News article provides viewpoints and data that conveys the added stress experienced by transgender and gender-nonconforming people when they are diagnosed with gender-associated cancer (e.g., ovarian or prostate cancer) that does not match their gender identity. (posted 9/13/21)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: High

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Update : Breast cancer disparities in Black Americans

Relevance: Medium-High

Strength of Science: High

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Most relevant for: Black women in the US

The American Association for Cancer Research (AACR) released a 2020 report about cancer disparities among racial and ethnic groups in the United States. In this review, we highlight findings on the burden of breast cancer in Black women. (posted 8/5/21)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

Study : Expanded access to Medicaid coverage under the Affordable Care Act is linked to reduced cancer mortality

Relevance: High

Strength of Science: Medium-High

Research Timeline: Post Approval

Most relevant for: People with breast, colorectal or lung cancer.

In 2014 the Affordable Care Act expanded Medicaid coverage. How did this affect healthcare for cancer patients? This study shows that deaths from breast, colorectal and lung cancer are lower in states that chose to expand Medicaid compared to states that did not. Early diagnosis was linked to lower death rates. This suggests that increased healthcare access may lead to earlier cancer detection and better outcomes, including lower mortality. (3/31/2021)

Este artículo está disponible en español.

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Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Study : How breast cancer patients experience hormone therapy

Relevance: Medium-High

Strength of Science: Medium-High

Research Timeline: Post Approval

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Most relevant for: Breast cancer patients taking or considering taking hormone therapy

Side effects from hormone therapy are a common reason that many men and women with hormone receptor-positive breast cancer stop treatment early. Some people never start hormone therapy. This study asked patients about their experiences with hormone (or endocrine) therapy. The results suggest that there may be ways to improve the number of patients who stick with therapy. Patients need better ways to manage hormone therapy-related side effects. (1/19/21)

Este artículo está disponible en español.

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Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Study : Trodelvy clinical trial results likely practice-changing for people with metastatic triple-negative breast cancer

Relevance: High

Strength of Science: High

Research Timeline: Post Approval

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Most relevant for: People with metastatic triple-negative breast cancer

The ASCENT study confirmed an earlier study and showed that the drug sacituzumab govitecan-hizy (Trodelvy) improves outcomes for people with previously treated metastatic triple-negative breast cancer. These results further support the use of Trodelvy as a standard therapy for patients with pretreated metastatic triple-negative breast cancer. (11/20/20)

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Relevance: Medium-Low

Strength of Science: Medium-High

Research Timeline: Animal Studies

Study : The buzz about honeybee venom: Promising early research to treat breast cancer

Relevance: Medium-Low

Strength of Science: Medium-High

Research Timeline: Animal Studies

Most relevant for: People with breast cancer particularly those with HER2-positive or triple-negative breast cancer.

Early research showed that melittin, an ingredient in honeybee venom, may be used to treat HER2-positive and triple-negative breast cancers. This study found that melittin can kill cancer cells. The chemotherapy drug docetaxel more effectively killed breast cancer cells in mice when combined with melittin. It is not known whether melittin would be safe or affect cancer growth in people. While promising, more research must be done before melittin could be used to treat people.  (11/10/20)

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Relevance: High

Quality of Writing: High

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Personal Story : Coping with chemotherapy-induced hair loss

Relevance: High

Quality of Writing: High

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Most relevant for: People who receive chemotherapy for cancer treatment

Ovarian cancer survivor Stephanie Hess shared her personal story about how she coped with hair loss. This XRAY review also includes treatments to reduce this common side effect of chemotherapy. (9/28/20)

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Relevance: Medium-High

Research Timeline: Post Approval

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Guideline : FDA issues alert on a drug combination to treat triple-negative breast cancer

Relevance: Medium-High

Research Timeline: Post Approval

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Most relevant for: People with metastatic triple-negative breast cancer

The immunotherapy drug Tecentriq (atezolizumab) is approved for use with Abraxane (nab-paclitaxel) to treat metastatic triple-negative breast cancer. Tecentriq is NOT approved for use with Taxol (paclitaxel). The Food and Drug Administration has issued an alert to doctors, researchers and patients warning that Tecentriq should not be used in combination with Taxol to treat patients with advanced triple-negative breast cancer. (09/18/20)

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