All XRAYs

15 May 2025

Study : Enhertu shows promising results for HER2-low and HER2-ultralow metastatic breast cancer

Most relevant for: People with HR-positive metastatic breast cancer

Recent study results show that a new targeted treatment works better than standard chemotherapy for people with metastatic hormone receptor-positive breast cancers with low or ultralow HER2 status. (Posted 5/15/25)

12 May 2025

Study : Impact of mental healthcare among those with increased pancreatic cancer risk

Most relevant for: People with hereditary pancreatic cancer risk or strong family history of pancreatic cancer

Pancreatic cancer is often aggressive and diagnosed at a late stage, which can lead to uncertainty and fear. For those at risk due to a genetic mutation or family history, access to surveillance and mental health support is essential to help manage the emotional impact.  (Posted 5/12/25)

30 April 2025

Study : Two immunotherapy drugs are better than one for some metastatic colorectal cancers

Most relevant for: People with unresectable or metastatic colorectal cancer that is MSI-High or dMMR

Combining two immunotherapy drugs is a more effective treatment for certain metastatic colorectal cancers than using either treatment drug alone. Used together, Opdivo (nivolumab) plus Yervoy (ipilimumab) slowed cancer growth in MSI-High metastatic colorectal cancers, a type of colorectal cancer often found in Lynch syndrome. The FDA approved this combined treatment for MSI-High metastatic colorectal cancer after progression with chemotherapy. (Posted 4/30/25)

23 April 2025

Study : Hereditary cancer mutations among people with multiple myeloma

Most relevant for: People with multiple myeloma or who have families with multiple myeloma

People with multiple myeloma who have inherited gene mutations are more likely to have had another cancer previously and may respond better to certain treatments than people with multiple myeloma who do not have inherited mutations. Individuals with an inherited BRCA1 and BRCA2 mutation may have a slightly increased risk for multiple myeloma, but more research is needed to confirm this. (Posted 4/23/25)

16 April 2025

Update : News from the FDA: Colorectal cancer screening and treatment

Most relevant for: People with colorectal cancer or at risk of colorectal cancer

This XRAY review is a summary of FDA colorectal cancer (CRC) updates in the last year, including education regarding CRC screening, three treatment drugs targeting different types of CRC and two colorectal screening tests. (Posted 4/16/25)

6 March 2025

Update : Ovarian suppression may reduce breast cancer recurrence

Most relevant for: Premenopausal women before or during early breast cancer treatment

Ovarian suppression—blocking estrogen production in the ovaries—can improve breast cancer outcomes in premenopausal women. This review provides information about ovarian suppression and describes who might benefit. (Posted 3/6/25)

Este artículo está disponible en español.

28 February 2025

Topic : Addressing the needs of young adults with breast cancer

Most relevant for: Young women with breast cancer concerned about survivorship issues

This update addresses common concerns faced by young adults with breast cancer, particularly fertility and childbearing, psychosocial health and treatment-related side effects. (Posted 2/28/25)

Este artículo está disponible en español.

26 February 2025

Study : Neighborhood affects prostate cancer risk in men of West African ancestry

Most relevant for: Men with West African ancestry

Black men of West African genetic ancestry have a much higher risk of developing prostate cancer than men of other races. The risk is even greater when they live in deprived or disadvantaged neighborhoods.  (Posted 2/26/25)

Este artículo está disponible en español.

13 February 2025

Study : Impact on sexual well-being among people with an inherited BRCA mutation

Most relevant for: People with an inherited mutation that increases cancer risk who are interested in sexual health

This study looked at sexual well-being in those with an inherited BRCA1 or BRCA2 mutation. Knowledge about having an inherited BRCA1 or BRCA1 mutation did not influence sexual health. However, menopause and cancer diagnosis was had a significant impact on sexual health and sexual function. (Posted 2/13/25)

Este artículo está disponible en español.

23 January 2025

Study : Risk of peritoneal cancer is low for people with an inherited BRCA mutation after surgery

Most relevant for: People with a BRCA1 or BRCA2 mutation who have had risk-reducing surgery to remove their ovaries

The risk of peritoneal cancer is low in people with an inherited BRCA1 or BRCA2 mutation after risk-reducing ovary removal (oophorectomy). The risk was even lower when risk-reducing surgery was done at a young age and after 2005 when removal of the fallopian tubes was included in the procedure. The findings of this research support the theory that like ovarian cancer, peritoneal cancer begins in the fallopian tubes and reinforces the age recommendation for surgery. (Posted 1/23/25)

Este artículo está disponible en español.