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CDH1: Options for Cancer Treatment

Learn about personalized treatment options for people with a CDH1 mutation. Stay up to date by signing up for our community newsletter.
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Cancer Treatment Options for People with Inherited Mutations

Surgical decisions for women diagnosed with breast cancer

Because of the risk for a second breast cancer diagnosis, women who are diagnosed with breast cancer who test positive for an in  may choose  mastectomy rather than and radiation. Mutation carriers who undergo mastectomy are less likely to develop a second breast cancer. 

Targeted therapies and other treatment options

Treatment options for people with a mutation depend on the type and of cancer. Currently there are no FDA-approved targeted therapies or guidelines developed specifically for treating cancer in people with a mutation. To learn more about standard of care treatment options for specific types of cancer, visit our section on Cancer Treatment by Cancer Type. People with cancer should talk with their doctor about testing to look for changes in the cancer which may affect their treatment options. 

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Last updated September 07, 2025